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Bio Innovation & Entrepreneurship

Percolated up to national agenda
1404_ 7/12/13 - He is involved with so much and he still has time to hear student concerns. We're talking to Dr. Arlen Meyers, about the CU Program of Bio Innovation and Entrepreneurship, basically a certificate program for graduate level, business, science, engineering, law, health professionals, who are interested in getting an idea to a patient. Dr. Meyers, and CU created the program because there was a gap in providing these students with the business skills needed to find a job. The NSF and the graduate school community has recognized the gap, and finally it's percolated up to a national agenda item. "So", says Arlen, "we have created a program to provide the knowledge, skills, abilities, experience and networks that these people need to interact with industry and get a job." It is Arlen's belief that entrepreneurs need four things to be successful: "They need education; they need experience, networks and they need money, We provide all four in the program." Listen for more about the program and the unique legal and regulatory environment for bio science and health innovation and entrepreneurship. It is probably the most regulated industry in the U.S. Arlen Meyers, MD, MBA, is a professor at the CU School of Medicine, Department of Otolaryngology and he is President/CEO of the Society of Physician Entrepreneurs. Part 4 of 4...
RELATED LINKS: Society of Physician Entrepreneurs || CU School of Medicine || TiE Rockies Colorado || Economy Builders || Podcast Directory || KEYWORDS: Arlen Meyers, MD, MBA, CU School of Medicine, Bio Integration, Business skills, SoPE, TiE Rockies, Colorado, Society of Physician Entrepreneurs, NSF, Graduate School, Community Invention, Innovation, > bytes=4034040
LISTEN TO: Arlen Meyers, MD, MBA; President/CEO, Society of Physician Entrepreneurs (SoPE)

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TBI is a major public health problem

Treatment and prevention of brain damage
1402_ 7/2/13 - Here's another win with CU TTO. Dr. Kim Heidenreich, Professor of Pharmacology and Neuroscience at the University of Colorado-School of Medicine, in collaboration with Dr. Greg Miknis and the team at the Colorado Center for Drug Discovery (C2D2) at CSU, have made great strides in developing novel therapies for the treatment and prevention of brain damage caused by traumatic brain injury (TBI). In 2007, Kim’s lab discovered that a very potent inflammatory mediator, normally not found in the central nervous system, is present in the brain after TBI. Kim discovered that if this inflammatory mediator is blocked, secondary injury to the brain and the deleterious effects of TBI can be prevented. Together, Kim and Greg have developed a novel series of compounds that can inhibit this inflammatory molecule. The project is now moving toward advanced pre clinical studies that if successful will bring the program one step closer to a clinically approved drug, benefiting victims of this growing unmet medical need. When Larry interviewed Kim and Greg which was arranged by Matt Pink, Licensing Manager for the Colorado University Tech Transfer Office many interesting and valuable points were discussed. You will learn about the incidence of TBI and concussion as well as appreciate why TBI is a major public health problem. This interview will hopefully provide HOPE for listeners who have experienced a TBI or health providers for TBI patients. There is increased nonfederal funding for TBI (GE and NFL gifts) that is focused on diagnosis of TBI via blood bio markers or neural imaging. This is great but we also need more funding for developing TBI treatments ...Listen for more...
RELATED LINKS: CU Technology Transfer Office || Traumatic Brain Injury || CU TTO Channel || TTO Blog || Colorado Center for Drug Discovery (C2D2) || Mastering Change || KEYWORDS:Kim Heidenreich, Greg Miknis, Neuroscience, University of Colorado-School of Medicine, Colorado Center for Drug Discovery, C2D2, CSU, Traumatic Brain Injury, Inflammatory Mediator, CUTTO, > bytes=6579412
LISTEN TO: Kim Heidenreich, PhD and Greg Miknis, PhD

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Innovation is a step further

What's the difference between an improvement and an innovation
1395_ 6/15/13 - Arlen Meyers, MD, MBA, a professor at the CU School of Medicine, Department of Otolaryngology and he is President/CEO of the Society of Physician Entrepreneurs.
Part 3 of 4... We're talking about innovation and Arlen says... "So, the issue is what is innovation? If you ask 100 people, you're going to get 100 different answers. So, here is Arlen's two cents..."First of all there is a difference between an idea, an invention and innovation. An idea is something that pops in your mind - that's the end of it. An invention is an idea reduced to practice. You make a sketch, you build a prototype - you actually start conceptualizing how this thing is going to look/taste/feel, it's reduced to practice. It could be a process or service, it doesn't necessarily have to be a product or goods. But innovation is a step further. Innovation is about creating value and value that someone is willing to pay you for, or exchange something of value which is usually money. So an invention doesn't do you any good unless someone is willing to give you money to use it or buy it. That's what innovation is. Now it's usually something new. An argument is what's the difference between an improvement and an innovation? And does that make a difference? Probably not, but an improvement is you take an old way of doing something and you improve it verses an innovation where you take a new way to try to make things better. Arlen said, "In my view the U.S. healthcare system has not been terribly innovative. In fact most of the biomedical industrial complex has not been terribly innovative." He went on to say if you look at the amount of money that goes into the top research and development funnel through NIH... Last year the FDA approved 39 new drugs - total. And that was the highest number in 50 years. So what we get out of the bottom for what we put in the top, are 39 new drugs. And, if you look at what are those drugs, a lot of them are ...listen for more...
RELATED LINKS: Society of Physician Entrepreneurs || CU School of Medicine || TiE Rockies Colorado || Economy Builders || KEYWORDS: Arlen Meyers, MD, MBA, CU School of Medicine, Otolaryngology, SoPE, TiE Rockies, Colorado, Society of Physician Entrepreneurs, Idea, Invention, Innovation, > bytes=4457015
LISTEN TO: Arlen Meyers, MD, MBA, President/CEO, SoPE

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There's Money, but No Access

The art of raising money has changed a great deal [2 of 4]
1387_ 6/1/13 - Arlen Meyers, MD, MBA, a professor at the CU School of Medicine, Department of Otolaryngology and he is President/CEO of the Society of Physician Entrepreneurs [SoPE]. Part 2 of 4...We're talking about money and Arlen says... "The problem is there isn't access to it and from the standpoint of not that there isn't enough of it, because there is. It's just a question of how do Colorado entrepreneurs; particularly in healthcare get their fair share. I think it's useful to provide an overview. What's happening is that because of all the dynamics, venture capital has shrunk in the state. That whole business model is coming into question. Community based innovation is driving innovation. Accelerators have accelerated and it's easier than ever to start a business. Unfortunately it's not as easy to scale and fund a business. For instance, statistics indicate that the number of businesses started in the United States, in terms of reflecting entrepreneurship has dropped. It is now about a-half million businesses created in the U.S. And that's a good news/bad news story because some people interpret that as the economy is improving, as the real estate bubble has broke and now is re-growing, people are actually getting employed and finding jobs and there is no need for them to start their own business. So I don't like it when people are relieved of that sense of urgency whether it's by the economy sense or whatever. Getting back to the money, the issues are; There's not enough of it in Colorado and we need to create ways to get our fair share. I think there are a couple of ways to do that. One is, we need to rethink how the government, that is state government provides incentives to fund new startups. Particularly at the community level - not top down but bottom up. Two, we need to do a better job marketing Colorado as a technology hub and going to the money. The old Louie Sutton. Now he is on the coast, so we need to do a better job of going to the coast to get the money. Three, we need to be more innovative as far as how we create whether it's a fund-to-fund, crowd funding, all of these things that we've talked about over the last 30 years...listen for more...
RELATED LINKS: Society of Physician Entrepreneurs || CU School of Medicine || TiE Rockies Colorado || Economy Builders || KEYWORDS: Arlen Meyers, MD, MBA, CU School of Medicine, Otolaryngology, SoPE, TiE Rockies, Colorado, Society of Physician Entrepreneurs, Myogen Gilead, bytes=4928473
LISTEN TO: Arlen Meyers, MD, MBA; President/CEO, Society of Physician Entrepreneurs (SoPE)

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Top Stories August 29, 2005 - Historical Perspective...

2005 History - Building Business in Colorado...
1378_ 4/19/2013 -  8/29/2005- HISTORY and perspective from 2005! We will transport you back to 2005 - eight years ago to listen to interviews and see tons of photos from 2005 business events. Just click on the Listen/Subject link and we can take you back. You will see the 100s of photos that are not found on other websites. Let us know what you think email [email protected].
LISTEN TO: Phil Weiser, Merc Mercure, Chris Johnson, Stan Feld...
Keywords: Stan Feld, M.D., Healthcare system, Merc Mercure, photonics, Chris Johnson, VoIP, Phil Weiser, political environment changes, Silicon Flatirons Center, University of Colorado, Law School

Autism incidence on the rise... why?

Autism incidence increasing, you can make a difference
1375_ 4/11/13 - A few weeks ago Kevin Custer spoke to us about his work with the Colorado Autism Society and their new CEO, James Buckles. This is a topic we need to be much more aware of. When we refer to autism, we refer to it as Autism Spectrum Disorder, because there is a wide range of developmental disabilities that cause impairment in the areas of social interaction and communication and behavior. So for that reason we may have somebody that is very high functioning and capable of doing really incredible things and maybe socially awkward - but you may have someone on the spectrum that is non-verbal and can't really communicate. So you have those two variations and everything between. It really is very challenging to understand autism. The autism rates have gone up. The CDC says it basically comes down to two things. We have a better educated, better informed population of medical providers, doctors, people who know and can recognize it. The other is there is just more autism - the incidence rate has increased. Autism is one of the few disorders that is not race specific, it has nothing to do with geography. The only unique element of autism is that it is four times more likely to occur in boys than girls. The incidence rates are the same in the U.S. as they are in all countries, developed and undeveloped. Kevin said, "For businesses wanting to get involved and support, the website, AutismColorado.org is the place to start. The biggest thing we see is to train your employees to understand what's going on. If you have more than seven employees, one of them has a family member with autism. If that is the case, you're going to want to understand how you can better support that employee. With our Autism 101 program, we'll come into your business and explain about it. Then contacting James to figure out how we can help your business give support back to the community as far as being an autism friendly business." The ASC has a 'Walk' coming up June 9th, and James said, "We'd love companies to think about getting involved in the Walk Program. What we find is once their employees get involved, they'll come forward and be excited about this opportunity, create a team around supporting the disorder of autism. It's just a valuable way for a company to give back and at the same time will see benefits from being involved." Listen for more information....
RELATED LINKS: Autism Society of Colorado || Walk || ASC Programs || Donate || Arc Capital Development || KEYWORDS: Walk for Autism, Kevin Custer, James Buckles, Autism Society of Colorado, autism spectrum disorder, autism friendly business. sensory friendly films, CDC, Beau Jo's, autism friendly environment, bytes=7426615
LISTEN TO: Kevin Custer & James Buckles, CEO, Autism Society of Colorado

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Strategic Equity firm, focused on education & healthcare...

Kevin Custer, 15-20 million people who need product and services

1371_ 4/5/13 - Kevin Custer serves as the president of the board for the Autism Society of Colorado, he also works on the national board of directors. and Kevin is the founding partner of Arc Capital Development, a strategic equity firm that focuses on education and healthcare. Strategic equity is different than private equity or venture capital in that we invest from $150,000 up to $1 million at a strategic time in a company, when it's time for them to get to the next inflection point. Different from venture capital - it's later stage than that, earlier than private equity. Larry asked, "Why education and why healthcare?" Kevin replied, "We see a convergence of those two. We look at the healthcare space and we specialize a lot in the development of the schools. We see that as an emerging market. When you look at a healthcare market, you look at the different service providers, be it hospitals, clinics, professionals prescribing or non-prescribing, even the consumers now are starting to look at that. One of the largest providers of healthcare services in the U.S., specifically for children is the U.S. School System, because every child starting at the age of three is eligible for services through the school system. What we've seen happen is that market really starting to emerge. Larry asked Kevin what he meant when he said 'emerging market'. Kevin said, "There has always been a need for products and services in the development of the school area. What we have seen happen, specifically with Autism, is fifteen years ago there were a couple hundred thousand people with Autism in the United States - now there's close to two million. Just our school system alone has had a 10X increase and they need services, they need products, they need adapting equipment, things like that. On top of that the CDC believes one in six people need some type of adaptive or assistive help in their daily life. That is people with developmental disabilities, they've had a stroke, traumatic brain injury, whatever it is, we see that as the emerging market. That's 15-20 million people, just in the U.S. who need product and services. Products and services have been around for a long time, but they've been very expensive and complicated to use." ...there's more...
RELATED LINKS: Arc Capital Development || Autism Society of Colorado || Autism Society National || Walk Page || ASC Programs || Donate || KEYWORDS: Kevin Custer, Arc Capital Development, Autism Society of Colorado, ASC Programs, Strategic Equity, Emerging Market, Social Express, Capital, bytes=5287082
LISTEN TO: Kevin Custer, Founding Partner, Arc Capital Development

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29th National Space Symposium...

Leonard Nimoy and Star Trek come to Colorado
3/20/2013 [832_ 4/26/10] - At the 26th National Space Symposium, Larry and Pat had an opportunity to have a discussion with Leonard Nimoy of Star Trek fame. But Nimoy is so much more than that. They decided to talk about other topics that help us learn more about him and what has shaped his character over the past 79 years as well as understanding his hot buttons. We started out by reflecting on some poetry Leonard read as 'whale song' was heard in the background...that was decades ago but it opened up insights to his current interests and concerns. When asked, Is there something businesses can do to motivate children?" His reply was an ouch. "I'm not a sociologist, I'm not a businessman, I can't speak intelligently about that. I'll tell you what I am concerned about; I'm concerned about how much television kids watch that is not uplifting, or educational or inspiring in any way. It's all about celebrity, and if you're celebrity, come and tell us about your celebrity. What have you accomplished? I'm a celebrity - I'm famous for having a lot of children, so I want a TV show - It's crazy. What we have descended to in our education, it's crazy! It's really sad, I could go on about that, I'm not going to." He had a great deal to say about advice he would give to someone following his career path. "The biggest fantasy, myth about my work, about being an actor is people who think a look will get you somewhere, be at the right place and time, that kind of thing - luck plays a big role, but I never believed that, not even as a teenager ...Education, it's all about education. Learn, learn, learn and devote yourself to a profession. Be professional about it." Larry asked, "Do you feel the U.S. is losing its position in terms of space?" Leonard replied, "Yes, I don't know to what degree this is true. I don't want to be an alarmist about this, but I do think we've got some work to do." We did end with a Vulcan salute. Listen for much, much more...   April 8th Begins 29th National Space Symposium...
Related Links: 29th National Space Symposium || Space Technology Hall of Fame® || National Space Symposium || Space Foundation || More About Nimoy || Keywords: Leonard Nimoy, Star Trek, Spock, Vulcan, National Space Symposium, Space Foundation, Education, Douglas S. Morrow Public Outreach Award 4/26/10 Chnl: News bytes: 5458968
LISTEN to Leonard Nimoy, aka Mr. Spock

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Tech Transfer proof-of-concept investments work

Tom Smerdon, success in marketing new ideas
1364_ 3/13/13 - From a business person's point of view, the Technology Transfer Office is one of the most important things that the university provides, for business, individual professors and students, with everything from awards and recognition but most importantly really helping them along when they come up with an idea. Larry is with Tom Smerdon, Interim Associate Vice President of the University of Colorado Technology Transfer Office in Boulder. Tom said, "There are a couple of the things I'd like to bring to the listeners attention. One, which we're really excited about, is the recent acquisition of a CU startup. F5 Networks has acquired LineRate Systems, a Colorado startup that’s developing technologies around what’s called software define networking. F5 noted that the networking technologies will help bring superior service agility, application intelligence, and programmability to software defined data centers. The thing that is exciting about this is, not only was this a startup basically out of Computer Sciences and Electrical Engineering here on the CU Boulder campus, but the company was also an early recipient of the Proof-of-Concept investment from the Tech Transfer Office. This was the first money into the company which really helped it acquire some critical equipment early on and facilitated the development of the technology that was later further developed in its Louisville office and ultimately the subject of the sale to F5. This is one of the success stories for Tech Transfer and we're really excited for the company and the founders. A couple of events that are coming up; we are doing our Tech Transfer Awards a little differently this year. Previously there had been a single awards event covering the system campuses held in Denver. This year we're going to have campus focused events, so we have the Boulder Awards event which is scheduled for April 1st. This is in conjunction with the Deming Center for Entrepreneurship. The program, Entrepreneurship Under the Microscope, is an evening event with a keynote speaker and we will be awarding the Inventor of the Year, New Inventor of the Year, and Company of the Year during a fun networking event with CU-Boulder faculty and students, and members of the Boulder entrepreneurial community. We have the second awards event planned... there's more...
RELATED LINKS: CU Technology Transfer Office || CU TTO Channel || TTO Blog || LineRate Systems || KEYWORDS: Tom Smerdon, Interim Associate Vice President, Tech Transfer Office, University of Colorado, Technology Transfer, LineRate Systems, F5, Awards, bytes=4401426
LISTEN TO: Tom Smerdon, Interim Associate Vice President. Tech Transfer, University of Colorado

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TTO Eyes-On Advanced Industries Acceleration Act

Tom Smerdon First to Invent Rule under the America Invents Act
1360_ 3/6/13 - Larry is in Boulder with Tom Smerdon, Interim Associate Vice President of University of Colorado Technology Transfer Office. "There are several interesting events that we're keeping an eye on. One is the upcoming implementation of 'The First to Invent Rule under the America Invents Act. This goes into effect on March the 16th. So this has required us to look at some of the provisional applications that are pending and accelerate the filing of the U.S. Utility Applications. We've been doing that as well as setting up some informational and outreach efforts to inform the faculty of this change. One of the exciting legislative initiatives that Tom and his team are keeping an eye on is the Advanced Industries Acceleration Act. This was recently introduced in the House as HB1001 and basically it would expand the current Bioscience Discovery and Evaluation Grant Program [the BDEG] which currently provides for state grant funding / proof-of-concept funding for bioscience technologies as well as grants for early stage bioscience companies. It would expand that to six other advanced industries in Colorado. These are advanced manufacturing, aerospace, electronics, cleantech energy and natural resources, infrastructure engineering and information technology. While we make some changes to the basic BDEG funding, the basic structure is preserved. So there would continue to be proof-of-concept grants that would go to research institutions - that definition has been expanded somewhat, but it would include the state research institutions, University of Colorado. It would also provide some company matching grant funding, although the match would now be one dollar from the state to two dollars from the company and it will also provide infrastructure funding as is currently provided under the BDEG program. There are some caps on those funding amounts but in the case of proposals that would involve more than one advanced industry, those caps are removed. But again, it's pending and we'll have to see what the final legislation looks like. we've been working closely with the Office of Economic Development and International Trade on some related advanced... there's more...
RELATED LINKS: CU Technology Transfer Office || CU TTO Channel || TTO Blog || CID4 || CBSA || KEYWORDS: Tom Smerdon, Interim Associate Vice President, Tech Transfer Office, University of Colorado, Technology Transfer, The First to Invent Rule America Invents Act., Biotech Technologies, Bio Science Discovery, Office of Economic Development and International Trade, Bioscience Discovery and Evaluation Grant Program - bytes=5151245
LISTEN TO: Tom Smerdon, Interim Assoc. Vice President, Tech Transfer Office, University of Colorado

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